1996 Volume 37 Issue 4 Pages 234-239_1
The preservative levels in commercial toothpastes for general, children's and medicinal uses were measured by GLC, and daily preservatives intake arising from brushing of the teeth in female students (20 years old) was calculated and compared to the intake from the diet.
The levels of benzoic acid (BA) were 810-4, 450mg/kg in toothpaste for general use, and 800-850mg/kg in that for children's use. Those of p-hydroxybenzoic acid (PHBA) esters in the toothpastes for genelal, children's and medicinal uses were 70-1, 370mg/kg, 170-520mg/kg and 350-450mg/kg, respectively.
When toothpaste for general use containing BA 4, 450mg/kg and PHBA-ethyl 1, 550mg/kg was used by 40 female students, the daily intake of BA was about 2.23mg, which was almost the same as that from the diet, whereas the PHBA-ethyl daily intake was about 1.10mg, which was considerably higher than that through the diet.
