小児耳鼻咽喉科
Online ISSN : 2186-5957
Print ISSN : 0919-5858
ISSN-L : 0919-5858
成長ホルモン治療中に扁桃肥大が増悪し重度の睡眠時無呼吸症を起こしたプラダー・ウィリー症候群の1例
染谷 知宏宮本 茂樹工藤 典代有本 友季子
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2004 年 25 巻 1 号 p. 37-39

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The patient is a six-year-old boy with Prader-Willi syndrome (PWS). He started GH therapy when he was five years of age. Although he showed mild sleep problems before GH therapy, he did not have upper airway obstruction. Nine months after the initiation of GH therapy, he began to show severe sleep apnea. Otorinolaryngologic study revealed marked enlargement of the adenoid. After adenoidectomy, he showed remarkable improvement in sleep apnea.
Although the causal connection between GH therapy and adenoid enlargement is not clear, in this patient, GH therapy might have been associated with the cause of airway obstruction.
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