Recently, emerging penicillin-resistant Streptococcus pneumoniae (PRSP) in children has become a serious problem. Here, we investigated the incidence and drug sensitivity of Streptococcus pneumoniae isolated from upper respiratory specimens obtained from children in our hospital for four years. We found the peak ages of PRSP-positive patients was one and four years of age. The number of patients who were positive for resistant strains (PRSP + PISP) was increased. Only LVFX, VCM, and REP showed 100% sensitivity against PRSP. It is important to consider whether the isolated PRSP is a“real”pathogen for diseases, and to use proper antibiotics to avoid the prevalence of multi-drug resistant PRSP.
