亜鉛ガラス含有グラスアイオノマーセメントが脱灰象牙質に及ぼす影響

抄録

  Purpose : The purpose of this study was to investigate the protective effect of a glass ionomer cement (GIC) consisting of fluoro-zinc-silicate glass filler (BioUnion filler, BUF) glass on the demineralization of bovine dentin.

  Materials and Methods : BUF containing GIC (CA ; Caredyne Restore, GC) and a conventional GIC (FU ; Fuji Ⅶ, GC) were used. Slabs of dentin from bovine teeth were sliced, shaped into a rectangular form, and immersed in 0.5 M ethylenediaminetetraacetic acid (EDTA) solution at 25℃ for 6 days, followed by storage in distilled water for 3 days. After demineralization, they were immersed in artificial saliva with and without the GIC specimens. The surfaces of each dentin specimen were observed using scanning electron microscopy (SEM) at an operating voltage of 10 kV. In addition, elemental analysis of the specimen surface layer was carried out using energy-dispersive X-ray spectroscopy (EDX).

  Results : After the EDTA treatment, the smear layer was removed and the opening of the dentin tubules was observed. The SEM images of the CA and FU groups showed a narrowing of the dentin tubules compared to the specimens after the EDTA treatment. In comparison to the SEM images of the CA and FU groups, exposure of collagen fibers in the intertubular dentin was observed in the CA group. The results of EDX analysis of the surface layers of the specimens C, N, and O were detected as major elements in all groups. In addition to the elements detected in the Control group, Al and Si were detected in the FU group, while Al, Si, Sr, F, and Zn were detected in the CA group.

  Conclusion : Zinc and calcium ions adsorb on the crystal lattice of carbonate apatite, the precursor of hydroxyapatite, but due to the difference in ionic radii, calcification proceeds by the adsorption of calcium ions through ion exchange after zinc ions are adsorbed. Thus, GICs containing BUF were considered to have the potential to promote remineralization in the dentin.