Kinetic Study of Alkaline Hydrolysis Reaction of 4′,4″-Diacetylated Phenolphthalein

Abstract

This study conducted a chemical kinetic and thermodynamic analysis based on a mechanism of ester hydrolysis of an alkaline aqueous solution of a novel ester: 4′,4″-diacetylated phenolphthalein, which is converted phenolic hydroxyl groups of phenolphthalein. Inspecting the compound as experimental materials for estimating chemical reaction kinetics revealed that various thermodynamic energy factors (activation energy, activation Gibbs free energy, activation enthalpy, activation entropy) were calculable in a short time. A practical trial on graduate students suggested that the experimental material is useful for studying thermodynamic physical quantity for reaction rates.