2024 Volume 39 Issue 2 Pages 157-162
A 46-year-old man with a 10-year history of hidradenitis suppurativa (HS) presented with a 5 cm wide, ulcerated, and granulomatous tumor in the perineum. Histopathology of the skin biopsy revealed squamous cell carcinoma (SCC). The patient underwent an en bloc resection of the perineal tumor and HS lesions, followed by skin flap reconstruction and split-skin grafting. The surgical margins were negative.
Three and a half years after the surgery was performed, the patient developed recurrent SCC in the perineum. The tumor was resected once more and the pelvic floor muscles were partially resected. The defect was reconstructed with split-skin grafting.
HS-associated SCCs are usually large and have a high recurrence rate. This case highlights the importance of long-term follow-up for patients with HS-associated SCC, even after surgical resection with negative margins.[Skin Cancer (Japan) 2024 ; 39 : 157-162]