A case of lung adenocarcinoma discovered during systemic examination for breast malignant melanoma

Abstract

A 67－year－old woman presented with a 7 × 7 cm black－colored tumor on the skin on the inferior－lateral aspect of the right breast. During a systemic examination, a 2－cm diameter tumor was found in the upper lobe of the right lung. Two months after the initial visit, the patient underwent a right upper lobectomy with regional lymph node dissection ; a month later, she underwent a malignant melanoma resection with a right axillary sentinel lymph node biopsy. The lung cancer was staged as pT1bN0M0, stage ⅠA2. The malignant melanoma, staged as pT4aN1M0, stage ⅢC, was 5 mm in thickness and had metastasized to a lymph node. Pembrolizumab was administered as post－operative chemotherapy for one year. No tumor recurrence was noted five years post－surgery, highlighting the importance of consideringtumor depth and the presence of metastases when determining the order of treatment during post－operative therapy.[Skin Cancer (Japan) 2024 ; 39 : 266－269]