2025 Volume 40 Issue 2 Pages 109-113
A 60－year－old man had been receiving oral cyclosporine at a local clinic for chronic eczema for 10 years. Three years earlier, a black macule had appeared on his vertex scalp and gradually enlarged ; however, he did not seek medical attention. Two years prior, it measured 2 cm ; however, its rapid growth over the following year led him to consult the referring physician. Partial biopsy suggested malignant melanoma, and the patient was referred to our department. During his first visit, we observed a coalescent black－and－erythematous nodule on the vertex and an irregularly bordered black patch contiguous with a red nodule on the right temporal scalp. Two punch biopsies of the temporal lesion confirmed malignant melanoma. As immunosuppressive therapy is known to increase the risk of cutaneous malignancies and long－term cyclosporine use is becoming more common, we report this case with a review of the literature.[Skin Cancer (Japan) 2025 ; 40 : 109－113]
