2026 Volume 41 Issue 1 Pages 18-25
Stewart-Treves syndrome is a rare cutaneous angiosarcoma arising from chronic lymphedema and is associated with a poor prognosis, aggressive local progression, and systemic metastasis. Herein, we report three cases treated at our institution. All the patients received systemic paclitaxel therapy. In one patient, transcatheter arterial embolization was performed to control refractory bleeding. The remaining two patients underwent intensity-modulated radiation therapy (IMRT). These multimodal treatments enabled temporary local disease control. Although the clinical course was rapidly progressive and the patient died within approximately 1 year, effective local control was achieved, which prevented a significant impairment in quality of life.[Skin Cancer (Japan) 2026 ; 41 : 18-25]
