A64-year-old man with Malignant hemangioendothelioma on the scalp and the face was successfully treated by combination therapy of rIL-2 injection, electron beam irradiation and surgical operation. One shot rIL-2 injection was conducted through the bilateral external carotid artery, followed by operation. On the operation, total scalp was excised and covered with free graft. As maintenance therapy, injection of rIL-2 has been performed 1-3 times a week.
