1997 年 12 巻 2 号 p. 192-195
Balloon cell melanoma, a rare variant of malignant melanoma, was firstly described by Gardner & Vazquez at 1970. We report a case of 56-year-old female with SSM type balloon cell melanoma on the skin. The tumor was mainly composed of atypical balloon cell nests involving into the deep dermis. Tumor thickness was 4mm. lmmunohistochemically, the tumor cells war strongly positive for S-100 and HMB-45, positive for NSE, and weakly positive for CEA. Wide local excision and therapeutic neck dissection were performed (pT4N1M0, stage III b). Until now the patient has been free of disease. We analyzed 7 cases in Japanese literature and 7+34 cases in English literature, and discussed the prognosis of balloon cell melanoma.