We reported a case of cutaneous T cell lymphoma. A 72-year-old woman had a two year-history of small red papules and diffuse erythema without scales on her whole body. Histologically, Pautrier's microabscess was found in the epidermis. She was treated with PUVA, IFN-γ and oral corticosteroid. One year later, her peripheral blood contained an increased number of atypical lymphocytes. INF-α, CHOP therapy and etoposide showed no improvement on her condition. Two years later, she died of the atypical lymphocyte infiltration on her whole body.
