A 70-year-old patient who presented with a black, reddish nodule on his scrotum was referred to our hospital in March 1994. Many inguinal lymph nodes were palpable. Under the clinical diagnosis of malignant melanoma, a wide local excision combined with a 4-5cm lateral margin including the external spermatic fascia and continuous superficial inguinal lymphadenectomy was performed. Histopathological diagnosis revealed nodular malignant melanoma of pT4bNOM0 (2002 UICC) with a tumor thickness of 13mm. After the surgical treatment the patient was treated with three cycles of DAV-feron biochemotherapy regimen and Bestatin for three years. At 7 years after the initial operation the patient is disease-free.
Primary malignant melanoma of the scrotum is a rare entity, with only 10 cases reported previously around the world. [Skin Cancer (Japan) 2003; 18: 70-74]
