2018 Volume 17 Issue 5 Pages 270-273
We report a case with an erlotinib-induced cutaneous adverse event with histopathology of subcorneal pustular dermatosis. A 62-year-old woman presented with numerous red papules on her lower limbs six months after starting erlotinib 100 mg/day for lung cancer. She developed eruptions on her lower limbs four months earlier, and red papules were associated with pustules, crusts and erosions. Histopathology from the acneiform eruption of the lower leg showed subcorneal pustules associated with neutrophilic inltrate. Hair follicles were not involved in the area of inammation around the pustule. She continued taking erlotinib with topical steroid treatment and oral minocycline 50 mg/day. Her eruption gradually disappeared without recurrence. Skin Research, 17 : 270-273, 2018
