Abstract
A 63-year-old female presented with one-month history of a nodule on her dorsum of the left foot. It grew gradually. There was no history of trauma. Physical examination revealed an oval, light brown, 12×9mm in size, elastic hard nodule. The nodule was biopsied under the clinical diagnosis of dermatofibroma. Histologically, multilobluar nests were observed around the blood vessel, nerve and eccrine gland apparatus. The tumor was composed of the spindle-shaped stromal cells and histiocytic cells without nuclear atypia and mitoic figures. These cells expressed CD34, but not factor XIII a and keratin. The tumor nests contained a number of capillaries, abundant mucin and the network of reticulum fibers. Based on these findings, the diagnosis of fibromyxoma was made.