Hifu no kagaku
Online ISSN : 1883-9614
Print ISSN : 1347-1813
ISSN-L : 1347-1813
CASE REPORT
Skin Metastasis of Prostatic Carcinoma
Yasuhiko YoshidaJun NagaoHiroshi KajikawaHideaki MiwaMasamitsu Ishii
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2006 Volume 5 Issue 3 Pages 223-226

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Abstract
The 69 year-old man presenting with skin metastasis from prostatic carcinoma is reported.
11 years ago, he had a diagnosis of prostatic carcinoma and metastasis to bone and then he had been treated with the hormonal therapy, radiotherapy and chemotherapy.
At first visit, he had presented some red colored firm skin nodules mainly in the scrotum part. Histopathological studies showed dermal nests consisted of atypical cells of non-cutaneous origin, which arranged in a glandular pattern. Immunohistochemical staining of those cells for prostatic specific antigen were positive.
At the time skin metastasis appeared, PSA rose in 980ng/ml and computed tomography showed wall of bladder infiltrated, metastasis to the pelvic and mediastinal lymph nodes and to liver. He died about two months later.
Prostatic carcinoma rarely metastasizes to the skin. But, we propose that this case will increase, because the prevalence rate of prostatic carcinoma is increasing dramatically.
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© 2006 Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association
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