Abstract
A 72-year-old man presented with a slow-growing, asymptomatic red nodule of a 2-year history on the right side of the scrotum. The lesion was a solitary, soft, and pedunculated nodule with a granular surface. The lesion was excised under local anesthesia. On microscopic examination, the specimen showed papillomatous elongation of the rete ridges and infiltration of form cells in the upper dermis. The dermis contained several dilated vessels. Based on these features, the diagnosis of verruciform xanthoma was made. Compared to other cases of verruciform xanthoma, we observed marked vascular ectasia in the dermis. This observation indicated that high vascular pressure may play a role in the pathogenesis of verruciform xanthoma.