Abstract
A 23-year-old man was seen with a 5-year history of multiple asymptomatic keratotic lesions which were distributed throughout the body except for head, palms and soles. Histopathologic examination of the biopsy specimen revealed the cornoid lamella. As patients with disseminated superficial porokeratosis(DSP) are predisposed to skin cancer, they should be fully evaluated periodically. At this time, there is no cure for DSP to inhibit malignant alteration. Further study of causative gene will explain the pathogenesis of this disorder which will lead to development of new treatments.