Feasibility of Automated Analysis of the Renal Microcirculation Using Synchrotron-Based Micro-Computed Tomography

Jennifer P. Ngo; Zohaib Khan; Roger G. Evans; Connie P. C. Ow; Masato Hoshino; Kentaro Uesugi; Bruce S. Gardiner; David W. Smith; James T. Pearson

doi:10.18957/rr.10.1.28

Section A

Feasibility of Automated Analysis of the Renal Microcirculation Using Synchrotron-Based Micro-Computed Tomography

Jennifer P. Ngo, Zohaib Khan, Roger G. Evans, Connie P. C. Ow, Masato Hoshino, Kentaro Uesugi, Bruce S. Gardiner, David W. Smith, James T. Pearson

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Keywords: microcirculation, hypoxia, kidney disease, vessel geometry, 2018A1289, BL20B2

JOURNAL OPEN ACCESS

2022 Volume 10 Issue 1 Pages 28-34

DOI https://doi.org/10.18957/rr.10.1.28

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Abstract

　We investigated the feasibility of visualizing and characterizing the spatial associations between vessels of the rat renal microcirculation using 3D images. We compared the quality of Microfil® and Micro-Angiofil® as filling mediums. 3D visualization of the blood vessels appeared promising, but we were unable to extract quantitative information on the microvessels from the images obtained.

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