To evaluate the clinical usefulness of a fibrin glue (Beriplast® P), which consists of human fibrinogen, thrombin, blood coagulation factor XIII, CaCl2 and aprotinin, a clinical trial was done in 21 cases.
This glue was used for the purpose of hemostasis, adhesion, packing and protecting of the wound, and revealed to be effective in hemostasis on the bone surface, packing of the dead space after cystectomy and protecting the raw surface of the grafted skin in the donner.
Although this glue seemed to be less useful for adhesion of a mucosal flap, its adhesive effect was excellent in attaching a lyodura to a bone defect of the orbital floor. Side effects of the fibrin glue were not recognized in all cases.
