2002 Volume 51 Issue 4 Pages 277-280
Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematopoietic disorders characterized by peripheral cytopenia and dysplasia of hematopoietic cells. To date, bone marrow transplantation is the only radical treatment, but this method is suitable for only the youth. Therefore, various other therapies have been applied to the management of MDS. We report the experience of a surgical procedure for a patient with MDS, who has been undergoing immunosuppressive therapy with cyclosporin.
The patient was a 49-year-old female. She wasreferred to the Department of Oral and Maxillofacial Surgery, Kobe Steel Hospital, Kakogawa, because of gingival enlargement induced by cyclosporin. Extraction of teeth and a gingivectomy were formed after hemostatic control by infusion of HLA-class I antigen-matched platelet concentrates. There were no findings of abnormal bleeding and infection during or after the operation, and the patient did well.