抄録
The effect of large dose ascorbic acid supplementation on hepatotoxicity and altered immunological parameters in alcoholics without apparent liver disease was investigated. Supplementation restored serum gamma glutamyl transpeptidase (GGT) activity, serum albumin and serum immunoglobulin levels, T and B cell numbers in the peripheral circulation and ascorbic acid amd dehydroascorbic acid levels both in plasma and leucocytes. This suggests an important role for ascorbic acid in combating free radical mediated damage and impaired immunological function in alcoholics.
