抄録
Dinoflagellates are the rich sources of huge polyol compounds. It is intriguing why dinoflagellates produce such huge and complex compounds. However, their physiological functions or roles in ecosystem are scarcely known. To solve this problem, it is needed to find more huge compounds and to clarify the mechanisms of their biological and physiological activities. In our continuous research about the polyol compounds, a novel huge polyol compound, amdigenol A, was isolated from the Okinawan dinoflagellate Amphidinium sp. The structural elucidation of amdigenol A was performed by the combination of 2D-NMR spectroscopic analyses, the chemical degradation with Grubbs catalyst, and ESI-MS/MS analyses. Amdigenol A, whose molecular weight was 2169 mass unit, was consisted of a C98-linear long carbon backbone with two exo-methylene and four methyl group including a sulfate ester, thirty-six hydroxyl group, and three tetrahydropyrans. The structural elucidation of amdigenol A should contribute to identify the other species of huge polyol compounds produced by the same dinoflagellate.
