The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Short Reports
An Evaluation of Neuromuscular Reversal with Edrophonium in a Patient with Malathion Intoxication
Shu Matsukawa, Yasuhiko Hashimoto, Masato Kato, Kunihiko Hoshi, Daizoh Satoh, Takashi Horinouchi, Shun Satoh, Toshio Saishu
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Keywords: malathion intoxication, edrophonium, cholinergic crisis, neuromuscular reversal
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1997 Volume 181 Issue 4 Pages 467-469

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Abstract
We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10 mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.
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© 1997 Tohoku University Medical Press
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