The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
Invited Review
Gene-Based Deafness Research: Ion Transport and Hearing
Katsuhisa Ikeda
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2004 Volume 202 Issue 1 Pages 1-11

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Abstract

The cochlea is a sensory organ that converts physical (sound) stimulation into electrical signals. This process is fundamentally and substantially based upon the ion transport system. Here, I summarize the physiological and molecular biological aspects of transporters, channels and receptors expressed in the cochlea. With reference to these findings, recent advances in genetic research on hereditary deafness are discussed.

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© 2004 Tohoku University Medical Press
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