2026 Volume 269 Issue 2 Pages 199-202
Hamartomas are abnormal tissue growths that can occur in various organs including the sinonasal tract. In this region, they are categorized into four subtypes, with respiratory epithelial adenomatoid hamartoma (REAH) being the most frequently reported. However, seromucinous hamartomas (SMHs) are rare, and only a limited number of case reports are available. This paper presents a case of an SMH located in the posterior nasal septum in a 45-year-old woman. The lesion was successfully excised in an outpatient procedure without complications. A pathological examination confirmed the diagnosis of SMH. At the three-month postoperative follow-up examination, no recurrence was observed and complete wound healing was noted, leading to the conclusion of follow-up. The continued accumulation of cases is needed to enhance the understanding of SMH, and it is important to recognize SMH as a potential differential diagnosis for tumorlike lesions in the sinonasal area. Although patient factors such as lesion location and comorbidities may influence treatment decisions, outpatient surgery can be a cost-effective option for SMHs when en bloc resection is feasible.