The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Effect of Phenoxybenzamine on the Relaxing Response of Taenia Coli
TAIZO SUZUKI, AKIRA RIKIMARU
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キーワード: phenoxybenzamine, relaxing response
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1970 年 102 巻 4 号 p. 415-416

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Phenoxybenzamine, α-adrenoreceptor blocking agent, produced the potentiation of the relaxing response of taenia coli to transmural stimulation. This potentiation effect was prevented in the presence of atropine. Moreover, the relaxing response caused by nicotine was abolished by phenoxybenzamine. These results imply that phenoxybenzamine has blocking actions on the muscarinic receptor and possibly on the nicotinic receptor, as well as the adrenergic α-receptor.

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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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