Abstract
The specific elution method has been used for investigating the presence and quantitation of blood group antigens on the surface of HeLa and S3 cells. S3 cells which had been cultivated independently in various laboratories constantly exhibited B blood group antigenicity, but wild HeLa cells, represented H antigenicity. Each of the cells contained M blood group antigen, but not N antigen. Possible mechanisms of the conversion of the antigen from H to B in S3 cells were discussed.