Abstract
The infusion of the canine pancreas in situ was performed under constant pressure. It was found that dopamine caused a profuse flow of pancreatic juice with a slight vasoconstriction depending on the doses ranging from 1 to 10μg. The secretory response of dopamine was also obtained by intravenous administration. The authors suggest that dopamine acts a definite physiological role in the secretory mechanism of the pancreas.
