1973 Volume 111 Issue 4 Pages 371-375
Adult male dogs were injected into the third ventricle (3 rd V) with graded doses of cateeholamines and indoleamines, and changes in secretion of testicular 17-oxosteroids by the testis were investigated for up to 2-4 hr after the injection. The secretion of testicular 17-oxosteroids was not affected by intraventricular treatment with 2, 5 and 10 μg of dopamine but stimulated slightly with 50 μg. The response was transient and occurred for up to 90min after the injection. Intraventricular injection of 50 and 100 μg of noradrenaline or adrenaline had no stimulatory effect nor did it significantly alter the secretion of 17-oxosteroids by the testis for up to 120min after the injection. Furthermore, serotonin and melatonin, given into the 3 rd V with doses of 5 and 50 μg, caused little or no secretion of testicular 17-oxosteroids.
