Histological Findings and Amylase Contents of the Pancreas and Parotid Gland of Rats with Experimental Obstruction of the Common Bile Duct

Abstract

In 10 control rats and 9 rats with common bile duct obstruction, histological studies were conducted on the pancreas and the parotid. Amylase activity was measured in these tissues and serum. The following results were obtained 1. After common bile duct obstruction, the parotid gland showed almost normal histological findings. 2. Amylase content of the parotid gland was normal after the common bile duct obstruction. 3. Serum amylase was decreased in the activity after the common bile duct obstruction. 4. In mild change in histological findings of the pancreas after bile duct ligation, the parotid gland showed no histological or functional changes. These results would rule out an influence, if any, of common bile duct obstruction on histology and function of the parotid gland.