The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Serum Levels of Diphenylhydantoin and Phenobarbital in Epileptic Children Receiving Diphenylhydantoin, Phenobarbital and/or Mysoline
TOSHIO YOSHIDAMINORU KARAHASHIMUNEYUKI TANABUTOKURO TAKAGITSUNEO ARAKAWA
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1974 年 112 巻 2 号 p. 169-175

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Out of 49 epileptic children treated with diphenylhydantoin and phenobarbital there were 36 cases with poor or partial control of seizures, among whom 20 cases had serum diphenylhydantoin levels below 5 γ/ml and 8 cases had serum phenobarbital levels below 10 γ/ml. Thus estimation of serum levels of each of drugs has proved to be a valuable guide in management of childhood epilepsy.

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© Tohoku University Medical Press
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