1974 年 112 巻 2 号 p. 169-175
Out of 49 epileptic children treated with diphenylhydantoin and phenobarbital there were 36 cases with poor or partial control of seizures, among whom 20 cases had serum diphenylhydantoin levels below 5 γ/ml and 8 cases had serum phenobarbital levels below 10 γ/ml. Thus estimation of serum levels of each of drugs has proved to be a valuable guide in management of childhood epilepsy.