Abstract
A new method is devised to show characteristic changes of hepatic sinusoids in hepatic cirrhosis. After a venous catheter was wedged into the hepatic veins and the wedged hepatic venous pressure was recorded, a contrast medium was slowly infused by gravity at a pressure which was slightly higher than the wedged hepatic venous pressure and was sufficient to flow slowly into the hepatic veins. By this method scattered nodules were shown in 74 per cent of the patients with hepatic cirrhosis, while uniform fine granular or reticular opacification of the sinusoids was observed in patients without hepatic diseases and in patients with hepatic diseases other than cirrhosis. Hepatic sinusoidography by this method is useful for the diagnosis of hepatic cirrhosis.