The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Bronchial Hypersensitivity to Methacholine in Monkeys with Beta-Adrenergic Blockade
SUETSUGU MUE, TADAO ISE, SHUNSUKE SUZUKI, MASAHARU SUGIYAMA, TAKAO SASAKI, TAMOTSU TAKISHIMA
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キーワード: bronchial hypersensitivity, beta-adrenergic blockade, monkey, methacholine
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1975 年 115 巻 4 号 p. 395-396

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In monkeys with beta-adrenergic blockade caused by administration of propranolol, we found that the conductance of the total respiratory system markedly decreased following in-travenous administration of methacholine. The presence of beta-adrenergic blockade was judged from inotropic effect on the heart, levels of blood glucose and lactic acid, and the reaction of eosinophils after adrenalin injection.

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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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