The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Changes in Plasma Levels of LH, FSH and Testosterone Following the Administration of Synthetic Luteinizing Hormone-Releasing Hormone to Cryptorchid Patients
SHOTARO MATSUDAMASAFUMI SHIRAISHIRO MITSUKAWAMAMORU NAKAMURAKENZO YONEZAWA
Author information
JOURNAL FREE ACCESS

1975 Volume 116 Issue 4 Pages 327-332

Details
Abstract

The levels of LH, FSH and testosterone of three adult groups consisting of normal subjects, unilateral and bilateral cryptorchids were compared before and after LH-RH loading. It was found that both groups of cryptorchid had comparatively high plasma base line levels for both LH and FSH, particularly high in the bilateral group; and both groups responded to LH-RH loading. This indicates that their hypothalamo-hypophyseal systems were probably functioning normally. The plasma base line levels of testosterone were higher in unilateral cryptorchids than in the control group, and lowest in the bilateral cryptorchid group. But the reaction of testosterone levels to LH-RH loading was generally poor in both groups of cryptorchids, suggesting that, in cryptorchid cases, unilateral and bilateral, the capacity of the testicle to secrete testosterone is generally depressed, freeing central suppression. This probably accounts for the high values of plasma LH and FSH observed in such patients.

Content from these authors
© Tohoku University Medical Press
Previous article Next article
feedback
Top