The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Cell-Mediated Immunity to Measles Virus in Subacute Sclerosing Panencephalitis
TATSURU YAMANAKA, SHUNZO CHIBA, TOORU NAKAO, NOBUHIKO OKABE, NOBUO TAKAHASHI, SETSUKO SAITO, TOORU KITAYAMA, HIROSHI MISHIMA, KANAHIRO KONNO, KAZUE FUJIWARA
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キーワード: cell-mediated immunity, SSPE, lymphocytotoxicity
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1977 年 122 巻 2 号 p. 175-181

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Four patients with subacute sclerosing panencephalitis were investigated for their specific cellular and humoral immunities against measles virus. Lymphocytotoxicity mediated by peripheral blood lymphocytes was evaluated with the colony inhibition test of target cells having measles antigen. The lymphocytes from two patients of subacute sclerosing panencephalitis (SSPE) specifically destroyed the carrier cells; however, no significant lymphocytotoxicity was observed in the other two patients. The result suggests the heterogeneity in cellular immune states in SSPE patients.
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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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