The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Serum Vitamin B12 Levels of Patients with Rheumatoid Arthritis
TADASHI IGARAI, YOZO NISHIMURA, KIJURO OBARA, SHIGERU ONO
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キーワード: rheumatoid arthritis, serum vitamin B12, hemoglobin, α1 and α2 globulin
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1978 年 125 巻 3 号 p. 287-301

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To elucidate the role of vitamin B12 in the formation of anemia in patients with rheumatoid arthritis, serum B12 levels were investigated in patients with rheumatoid arthritis, patients with osteoarthritis and normal subject. Serum B, , level in patients with rheumatoid arthritis was significantly higher than that in patients with osteoarthritis and normal subjects. Serum B12 level increased in proportion to Steinbrocker's stages, and was related more closely to hemoglobin concentration than to erythrocyte count and had a high correlation with α1- and α2-globulin.
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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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