Abstract
The antimetastatic effect of Triton WR 1339 (TWR), a nonionic detergent, was evaluated in the rats bearing ascites tumor (Yoshida sarcoma or AH 66F). TWR did not inhibit the growth of primary tumor (ascites production). However, a marked inhibition of metastasis was observed in the lung and liver of rats treated with TWR. The results obtained suggest that TWR exerts antimetastatic effect before the entry of tumor cells into vascular channels. With other tests, it was found that TWR inhibits the release of tumor cells from tumor graft.
© Tohoku University Medical Press
Favorites & Alerts
Altmetrics
Recently visited articles
- Mechanically Induced Vasospasm and Postoperative Cerebral Infarction after Coil Embolization of Unruptured Cerebral Aneurysms in Anterior Circulation
- Four Novel Metabolites from Microbial Transformation of Curcumol by Cunninghamella blakesleana
- 精神疾患と自殺に係わる社会的要因に関する研究
—都道府県別解析による精神疾患の現状把握— - Synergism between Methamphetamine and Alcohol in a Case of Methamphetamine Psychosis
- Severe Maxillary Medication-related Osteonecrosis of the Jaw
- About this Journal
The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology. - Submitted manuscripts will be screened for
plagiarism with Similarity Check (https://www.crossref.org/services/similarity-check/).
Announcements from publisher
- Subscriptions
Inland subscriptions should be sent to Tohoku University Medical Press, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, JAPAN.
Subscriptions from abroad should be addressed to MARUZEN CO., LTD., EXPORT DEPARTMENT, Postal address: P.O.Box 75, Shinagawa, Tokyo 140-8799, JAPAN.
e-mail: export@maruzen.co.jp
Share this page