The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Immunotherapy of Autochthonous Rat Methylcholanthrene-Induced Sarcomas with a Mixture of Allogeneic Tumor Cells and BCG-CWS
HAJIME KUDOMICHIO SUGATAKASHI WAGAMASAMICHI OGASAWARATATSUSUKE SATOISAMU USUBUCHI
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1980 年 130 巻 1 号 p. 49-53

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Experimental immunotherapy with a mixture of allogeneic tumor cells and BCG cell-wall skeleton (BCG-CWS) was carried out against established autochthonous fibrosarcomas induced by 3-methylcholanthrene (MCA) in the subcutaneous tissue of rats. The inhibitory effect on growth in the early stage, tumor-size up to 2 cm in diameter, was significantly observed. No significant difference, however, was shown as compared with the effect of treatment with allogeneic tumor cells alone. That is to say, a more effective inhibition of growth due to the addition of BCG-CWS was not demonstrated.
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© Tohoku University Medical Press
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