抄録
The arterial smooth muscle cells and subcutaneous fibroblasts obtained from normal rats were cultured in the insulin-deprived and insulin-enriched medium with different glucose concentrations (1mg/ml, 3mg/ml and 5nag/ml) and the glucose uptake by these cells was observed for the period of 48 hr. Glucose uptake by the two mesenchymal cells was similarly highest during the first 12 hr and continued to keep at a constant rate during the 48 hr irrespective of the medium glucose concentrations and insulin addition. There were no differences between the smooth muscle cells and the fibroblasts in either the rate or the pattern of glucose uptake. The limited rate of glucose uptake in these cells suggests that hyperglycemia does not play an important role in the metabolic derangement of the mesenchymal cells or perhaps in the etiology of diabetic angiopathy.
