The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
The Effect of Actinomycin D on Serum Gonadotropin Response Patterns to Continuous LH-RH Infusions
TAKESHI YOSHIDAYUTAKA HATTORIHIROSHI SUZUKIKIICHIRO NODA
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1980 年 131 巻 1 号 p. 89-93

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Serum gonadotropin response patterns to LH-RH infusions were investigated in women with and without actinomycin D treatment. LH and FSH levels increased until 60min in the nonovarectomized premenopausal women and until 120min in ovarectomized women after infusion in both groups. But, thereafter the levels in women untreated with actinomycin D were much higher than in women treated with actinomycin D. These results support the view that the LH-RH-stimulated -synthesis of gonadotropin involves increased RNA synthesis.
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© Tohoku University Medical Press
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