Abstract
SAGISAKA, K., YOKOI, T., YAMASHINA, M., TANAKA, H. and MATSUMOTO, H. A Family Study of an Extremely Rare Rh-Hr Variant (-D-/-D-) in Two Generations. Tohoku J. exp. Med., 1982, 136 (3), 319-322 - A rare variant (-D-/-D-) in two generations due to consanguineous marriage was reported. The propositus (T.M., 27 years of age) delivered her second baby who suffered from severe jaundice. She had agglutinin of titer 1:64 in saline and 1:1, 024 in Coomb's test against red cells of her husband (CDe/cDE). Family study revealed that T.M's father and his two siblings were grouped as -D-/-D-. Each of the siblings (both females, 53 and 46 years of age) had three children who were delivered normally without hemolytic disease. No agglutinin concerning the Rh-Hr system was detected in the sera of the siblings.
