1983 Volume 139 Issue 4 Pages 423-424
NAKAGOMI, O., KUTSUZAWA-NAKAGOMI, T., SUTO, T., KONNO, T. and ISHIDA, N. Glycoprotein of Human Rotavirus Wa Strain Grown in MA104 Cells. Tohoku J. exp. Med., 1983, 139 (4), 423-424 - Eight distinct polypeptides with molecular weights of 130, 000 (130K, VP1), 96K (VP2), 84K (VP3), 80K (VP4), 56K (VP5), 40K (VP6), 35K (VP7) and 28K (VP8) were identified in human rotavirus (Wa strain) particles. Only VP7 was glycoprotein possessing high-mannose type oligosaccharide chain(s). Tunicamycin markedly suppressed the incorporation of [3H]glucosaminein to the VP7. This glycosylation pattern is very similar to that reported in simian rotavirus SA11.
