The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
T-Cell Subsets Analyzed by Monoclonal Antibodies in Patients with Primary Immunodeficiency Diseases
MASAYOSHI MINEGISHISHIGERU TSUCHIYAMASUE IMAIZUMIYOSHIKO YAMAGUCHITASUKE KONNOKEIYA TADA
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1984 年 142 巻 3 号 p. 231-238

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MINEGISHI, M., TSUCHIYA, S., IMAIZUMI, M., YAMAGUCHI, Y., KONNO, T. and TADA, K. T-Cell Subsets Analyzed by Monoclonal Antibodies in Patients with Primary Immunodeficiency Diseases. Tohoku J. exp. Med., 1984, 142 (3), 231-238 - The proportion of T-cell subsets was normal in all patients with X-linked agammaglobulinemia except for an 8-month patient who showed a decrease in OKT8+ T-cell population. In two patients with hypogammaglobulinemia with IgM production, T-cell subsets were normal in distribution and the patients' B cells produced only IgM in culture with autologous T cells. A patient with common variable immunodeficiency showed no imbalance in distribution of T-cell subsets. Imbalance of regulatory T-cell subsets was found in a patient with DiGeorge syndrome and severe combined immunodeficiency.
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