Abstract
MARUMO, F. Guanylylimidodiphosphate Enhances the Vasopressin- and Vasotocm-Induced Osmotic Water Flow with No Effect on the Sodium Transport of the Frog Bladder. Tohoku J. exp. Med., 1984, 144 (2), 183-188-The effects of guanylylimidodiphosphate [Gpp (NH) p] on the vasopressin- and vasotocin-induced osmotic water flow and sodium transport across the bladder of the frog, Rana catesbiana, were examined. Gpp (NH) p enhanced both the vasopressin-and vasotocin-induced water flow, while it did not affect that of the sodium transport. These results suggest that the neurohypophysial hormone-induced water flow is regulated by the guanine nucleotide regulatory site of the adenylate cyclase, while the sodium transport is not regulated at the regulatory site.
