Abstract
YAMAGUCHI, S., OKUNO, A., ETO, Y. and MAEKAWA, K. Pathochemical Study of a Case of Hereditary Cerebral Degenerative Disease-Lipopigment Accumulation and Peroxidase Deficiency in Brain. Tohoku J. exp. Med., 1985, 145 (2), 223-229 -Ultrastructural study of autoptic cerebral tissue from a patient with hereditary degenerative disease of the nervous system revealed lipofuscin-like bodies and variable sized osmiophilic granular masses in neurons. Autofluorescent granules were also found in neurons. Biochemical study demonstrated a deficiency of diaminobenzidine peroxidase and the accumulation of lipopigment in cerebral tissue.
