The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
A Note on the Effect of Haemorrhage upon the Blood Coagulation Time in Rabbits
BUNKICHI KAMEI
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1930 Volume 15 Issue 5-6 Pages 547-557

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Abstract
The coagulation time was determined for the bloods from the fastened rabbits before and after bleeding by means of Hirayama's modification of the graphic coagulometer of Cannon and Mendenhall.
The accelerating action of bleeding upon the clotting was infrequently detectable in normal rabbits when one eighth of the total blood amount was shed. The double splanchnicotomy was found to facilitate the manifestation of this action in the cases of bleeding of a similar amount of blood.
With the magnitude of bleeding the acceleration in the blood coagulation increased in the consistency of occurrence and in the severity, roughly speaking. However this rule can not be applied to the coagulation time study with such certainty as in the case of the hyperglycaemia due to bleeding.
Further in the instances of one third of the total blood amount, a certain relation was perceived to exist, though not so decidedly, between the velocity with which the blood flowed out and the shortening of clotting.
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© Tohoku University Medical Press
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