抄録
KONO, H., FURUHASHI, N., SHINKAWA, O., TAKAHASHI, T., TSUJIEI, M. and YAJIMA, A. The Maternal Serum Cortisol Levels after the Onset of Labor. Tohoku J. exp. Med., 1987, 152(2), 133-137 - We measured maternal cortisol levels after the onset of labor. Blood from 82 primiparas and 48 multiparas were collected 124 times and 60 times, respectively. When duration of labor was within 3hr, there were no differences in cortisol levels between the primiparous (n=11, 50.4±7.0μg/100ml, mean±S.E.) and multiparous (n=14, 37.8±4.3μg/100ml). However, when duration of labor was from 3 to 6hr, cortisol levels in the primiparas (n=20, 59.7±5.1μg/100ml) were significantly (p<0.05) higher than those in the multiparas (n=22, 46.8±2.9μg/100 ml). In cases of duration of labor from 6 to 9, cortisol level of the primiparas (n=24, 64.3±4.4μg/100ml) were also significantly (p<0.05) higher than those in multiparas (n=12, 49.4±4.7μg/100 ml). When duration of labor was more than 9hr there was no significant difference in cortisol level between the primiparas and multiparas. Maternal cortisol level had a significant (p<0.01) negative correlation (n=166, r=-0.243, Y=-0.09X+30.47) with unconjugated estriol level. These data suggest that maternal cortisol levels after the onset of labor are slightly different between the primiparous and multiparous, and that maternal unconjugated estriol levels decrease owing to reduction of the feto-placental blood circulation accompanied with uterus contraction during labor.
