The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Non-Invasive Adenomatous Component in Carcinoma of Papilla of Vater: An Immunohistochemical Study of Carbohydrate Antigen, CA19-9
HIDEMI YAMAUCHIATSUSHI NITTARYO ICHINOHASAMATSUNEO NAMIKI
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1989 年 159 巻 1 号 p. 81-82

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YAMAUCHI, H., NITTA, A., ICHINOHASAMA, R. and NAMIKI, T. Non-Invasive Adenomatous Component in Carcinoma of Papilla of Vater: An Immunohisto-chemical Study of Carbohydrate Antigen, CA19-9. Tohoku J. Exp. Med., 1989, 159 (1), 81-82-Eleven patients with carcinoma of papilla of Vater accompanied by non-invasive adenomatous component (nac) had good prognosis after surgical resection. These carcinomas were associated with low serum CA19-9 levels seldom invaded or metastasized to the pancreas, duodenum, lymph node and vein. On the contrary, 12 patients whose carcinomas lacked in `nac' had poor prognosis after resection. The `nac' negative carcinomas invaded or metastasised more frequently to the pancreas, duodenum, lymph node and vein. A half of the `nac' negative carcinoma showed high serum level of CA19-9. A significant different immunohistochemical pattern of CA19-9 was demonstrated between the `nac' positive and negative carcinomas. The former showed partial, while the latter showed diffuse distribution pattern.
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