The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Individual Identification of Human Bloodstains Investigated with Hypervariable DNA Loci
TSUYOSHI YOKOI, TOSHIO KIMURA, KAORU SAGISAKA
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キーワード: forensic science, bloodstains, hypervariable DNA loci, individual identification
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1990 年 161 巻 1 号 p. 9-18

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YOKOI, T., KIMURA, T. and SAGISAKA, K. Individual Identification of Human Bloodstains Investigated with Hypervariable DNA Loci. Tohoku J. Exp. Med., 1990, 161(1), 9-18 - Seven kinds of hypervariable DNA probes, which recognize hypervariable loci, were applied for individual identification of human bloodstains. Allelic frequencies and their confidence intervals among unrelated Japanese individuals were previously reported from our laboratory, and codominant segregation of the polymorphism was confirmed in family studies. One-month-old bloodstains from ten individuals were investigated in the present study. The probability of matching was calculated using the database among Japanese population. Cumulative probability of matching from 7 kinds of hypervariable DNA probes was 1.1×10-11, which was 4.5×109 times higher than that from 6 kinds of common blood group markers such as ABO, MN, Rh-Hr, P1, Hp and PGM1. Accordingly, DNA polymorphism is considered to be informative enough for individual identification of bloodstains.
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